Alcohol Related Cancer Deaths Have Doubled in the US Since 1990
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Alcohol Related Cancer Deaths Have Doubled in the US Since 1990

New research reveals that alcohol-related cancer risks are widespread, affecting diverse groups and a variety of different disease types.

By David Anderson
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A person holds a glass of alcohol as red and blue light illuminate the scene.

Surging Alcohol-Linked Cancer Mortality Rates Prompt Urgent Health Warnings

Deaths attributed to alcohol-related cancers in the United States have seen a dramatic escalation over the last three decades, effectively doubling between 1990 and 2023. A comprehensive analysis, published in The Lancet Regional Health—Americas, reveals that the annual toll of these preventable deaths climbed from 11,361 to 23,126 during the study period.

The research, which utilized over 30 years of data from the Global Burden of Disease study, underscores a growing public health crisis. While the link between alcohol and liver disease is historically well-documented, experts emphasize that alcohol is a Group 1 carcinogen, classified alongside asbestos and tobacco smoke by the International Agency for Research on Cancer. This classification highlights its role in the development of breast, colorectal, esophageal, pancreatic, and various head and neck cancers.

A Shift in Understanding Cancer Risk

The findings indicate that while individuals aged 55 and older and men remain the most heavily impacted, the influence of alcohol on cancer mortality is expanding across diverse demographics and regions. Chinmay Jani, chief fellow in hematology and oncology at the University of Miami’s Sylvester Comprehensive Cancer Center and the study’s corresponding author, noted that the breadth of the impact across various organ systems was particularly striking.

“Although its relationship with liver cancer is widely recognized, its contribution to cancers such as colorectal, esophageal, breast, pancreatic, and prostate cancer is less well understood by the public,” Jani explained. In older men, liver cancer remains the leading cause of alcohol-attributable mortality, while breast cancer stands as the primary driver of such deaths among women.

Emerging Trends in Younger Populations

Perhaps most concerning is the shift in mortality patterns among younger adults. For men between the ages of 20 and 54, colorectal cancer has overtaken liver cancer as the primary cause of alcohol-linked cancer death. Similarly, among women in this age bracket, breast cancer holds the top spot, with colorectal cancer following as the second most frequent cause of mortality.

The study also highlighted significant regional disparities across the United States. Data from 2023 shows that Washington, D.C., experienced the highest rates of alcohol-attributable cancer deaths, while Utah reported the lowest.

Prioritizing Prevention and Awareness

Despite the robust scientific evidence linking alcohol consumption to increased cancer risk, public awareness remains limited compared to the well-established dangers of tobacco. Researchers argue that addressing this knowledge gap is a vital step in improving long-term health outcomes.

Gilberto Lopes, senior author of the study and chief of the division of medical oncology at the Miller School of Medicine, emphasized that healthcare providers have a critical role in framing alcohol as a modifiable risk factor. “As physicians and cancer researchers, we have an opportunity to help patients understand that alcohol is a modifiable risk factor and that even small, informed changes can be part of a broader strategy to reduce cancer risk in our community,” Lopes stated.

While the scientific community has yet to determine a definitive “safe” threshold for alcohol consumption, the researchers conclude that reducing intake remains a clear and actionable strategy for individuals looking to mitigate their personal cancer risk. The study serves as a call for more targeted education, prevention, and early detection efforts to combat this rising trend in cancer-related mortality.

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Reference(s)

  1. Jani, Chinmay T.., et al. “Alcohol-attributable cancer mortality in the United States, 1990–2023: a secondary analysis of Global Burden of Disease data.” The Lancet Regional Health - Americas, September 1, 2026, pp. 101599 Elsevier BV, doi: 10.1016/j.lana.2026.101599. <https://doi.org/10.1016/j.lana.2026.101599>.

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Anderson, David. “Alcohol Related Cancer Deaths Have Doubled in the US Since 1990.” BioScience. BioScience ISSN 2521-5760, 14 September 2026. <https://www.bioscience.com.pk/en/subject/health/cancer-deaths-tied-to-alcohol-doubled-between-1990-and-2023>. Anderson, D. (2026, September 14). “Alcohol Related Cancer Deaths Have Doubled in the US Since 1990.” BioScience. ISSN 2521-5760. Retrieved September 14, 2026 from https://www.bioscience.com.pk/en/subject/health/cancer-deaths-tied-to-alcohol-doubled-between-1990-and-2023 Anderson, David. “Alcohol Related Cancer Deaths Have Doubled in the US Since 1990.” BioScience. ISSN 2521-5760. https://www.bioscience.com.pk/en/subject/health/cancer-deaths-tied-to-alcohol-doubled-between-1990-and-2023 (accessed September 14, 2026).
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