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Scientists Just Overturned a Rule of Aging by Flipping One Genetic Switch
https://www.bioscience.com.pk/en/subject/genetics/scientists-just-overturned-a-rule-of-aging-by-flipping-one-genetic-switchbuilt a large screening system called the Transcriptional Rejuvenation Discovery Platform. They started with human skin fibroblasts grown in the lab. Young fibroblasts divide actively and function well. Old fibroblasts slow down and show many features...
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Stanford Researchers Created a Virtual Biotech Company Run by 37,000 AI Agents
https://www.bioscience.com.pk/en/subject/biotechnology/virtual-biotech-company-puts-37-000-ai-agents-to-work-on-drug-discoveryasked to evaluate the B7-H3 protein, the AI agents correctly hypothesized that the protein’s presence in tumor-associated fibroblasts suppressed local immune responses. Based on this, the system proposed a targeted antibody-drug conjugate to neutralize...
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B7-33: A Biased Peptide Signal in the Expanding Landscape of Relaxin Receptor Research
https://www.bioscience.com.pk/en/topics/biotech-industry/b7-33-a-biased-peptide-signal-in-the-expanding-landscape-of-relaxin-receptor-researchHow a truncated relaxin-2 derivative is reshaping questions about receptor bias, selective signaling, and the future of pathway-specific peptide research. Within the intricate signaling architecture that governs cellular communication, few peptide...