(compound of three Greek words: ἱστός histos
", πάθος pathos
"suffering", and -λογία -logia
"study of") refers to the microscopic examination of tissue in order to study the manifestations of disease. Specifically, in clinical medicine, histopathology refers to the examination of a biopsy
or surgical specimen by a pathologist
, after the specimen has been processed and histological sections have been placed onto glass slides. In contrast, cytopathology examines (1) free cells or (2) tissue micro-fragments (as "cell blocks").