A single whole blood donation can be separated into different components to provide treatment to more than one patient. One unit of whole blood can be broken down into one…
The organisms likely to be transmitted by transfusion are usually those, which are prevalent in a particular geographic area or population.
Blood transfusion is a life-saving procedure in an appropriate setting and there are no side-effects in the majority of cases. However, it is a potentially harmful procedure and every recipient…
This is done by flow cytometric analysis for detection of lack of GpIb/IX in Bernanrd Soulier syndrome (deficiency of CD42), and lack of GpIIb/IIIa in Glanzmann’s thrombasthenia (deficiency of CD41,…
D-dimer is derived from the breakdown of fibrin by plasmin and D-dimer test is used to evaluate fibrin degradation. Blood sample can be either serum or plasma. Latex or polystyrene…
FDPs are fragments produced by proteolytic digestion of fibrinogen or fibrin by plasmin. For determination of FDPs, blood is collected in a tube containing thrombin (to remove all fibrinogen by…
Automated hematology analyzers work on different principles:   Electrical impedance Light scatter Fluorescence Light absorption Electrical conductivity.   Most analyzers are based on a combination of different principles.   (1)…
AUTOMATED HEMOTOLOGY ANALYZER Automation is a process of replacement of tasks hitherto performed by humans by computerized methods. Until recently, hematological tests were performed only by manual methods. These methods,…
CAUSES OF ERRONEOUS RESULTS (INTERFERENCES CAUSING ABNORMAL RESULT)   These are listed in Table 809.1   Table 809.1 Causes of erroneous results with hematology analyzer Parameter Interfering factors   Erroneous increase…
Parameters measured by hematology analyzers and their derivation are shown in Tables 808.1 and 808.2. Most automated hematology analyzers measure red cell count, red cell indices (mean cell volume, mean…
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