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A fluorescence microscope is an optical microscope that uses fluorescence and phosphorescence instead of or in addition to reflection and absorption to study properties of organic or inorganic substances. The 'fluorescence microscope' refers to any microscope that uses fluorescence to generate an image whether it is a more simple set up like an epifluorescence microscope or a more complicated design such as a confocal microscope which uses optical sectioning to get better resolution of the fluorescent image.